8 Cheapest GLP-1 Providers (2026)
GLP-1 prices vary by a factor of ten depending on molecule, brand vs. compounded, and provider. Here is the verified all-in cost comparison across the most accessible options.
The cheapest legitimate GLP-1 in 2026 is compounded semaglutide from Henry Meds at roughly $249/mo for the oral form or $297/mo for the injection — all-in with visits and shipping. Compounded tirzepatide starts around $199/mo at its most affordable (Curex). Brand-name options through LillyDirect (Zepbound vials) start at $299/mo for the lowest dose. Brand-name Wegovy through NovoCare intro pricing starts at $199/mo for starter doses but climbs quickly. All GLP-1 programs are cash-pay only or require specific insurance. Every price below is dated June 2026; the regulatory environment for compounded versions is active — re-verify before enrolling.
What you'll actually pay
| Provider | Price / mo | Notes | |
| Henry Meds (compounded semaglutide)cheapest compounded sema* | $249–$297/mo* | Compounded 503A, fully bundled — medication, visits, supplies, shipping. Oral semaglutide from $249/mo; injection from $297/mo. No titration price hikes. Cancel monthly. | See |
| Fridays (compounded semaglutide) | $150–$249/mo* | Compounded 503A, bundled with coaching, dietitian and app. Month-to-month ~$249/mo; 12-month commitment ~$150/mo. Tirzepatide: $240–$359/mo on same schedule. | See |
| Curex (compounded tirzepatide)cheapest all-in tirzepatide* | ~$199/mo* | Compounded 503A tirzepatide, all-in including medication, consult and shipping, no separate membership. Cheapest legitimate tirzepatide all-in we can verify. | See |
| NovoCare (Wegovy starter) | $199 → $349–499/mo* | Brand-name semaglutide (Wegovy). $199/mo intro for first two starter fills (0.25mg–0.5mg); rises to $349/mo at 0.5–1mg Ozempic; $499/mo at 2mg. Must be new to NovoCare savings program. | See |
| LillyDirect (Zepbound vials)brand reference | $299–$449/mo* | Brand-name FDA-approved tirzepatide (Zepbound) as self-pay vials: $299 (2.5mg), $399 (5mg), $449 (7.5–15mg). Must refill within 45-day window; outside window prices rise to $499–$699. | See |
| Mochi Health (compounded tirzepatide) | ~$278/mo* | Compounded 503A tirzepatide: $199 medication + ~$79/mo membership = ~$278 all-in. Flat price across all doses. | See |
| Ro Body (brand-name semaglutide) | $149 + ~$145/mo membership* | Ro offers brand-name Wegovy via NovoCare. Introductory pricing at $149/mo for Wegovy oral starter; membership adds ~$145/mo. Total at intro rate: ~$294/mo. | See |
| Hims & Hers (brand-name semaglutide) | $249 + $149/mo membership* | Oral Wegovy from ~$249/mo; injectable Wegovy ~$299/mo. Membership $149/mo billed separately. No compounded semaglutide for new patients as of March 2026. | See |
Two different products: what you need to understand first
'GLP-1' covers a class of medications, not a single drug. The two most relevant in 2026 are semaglutide (Ozempic, Wegovy) and tirzepatide (Zepbound, Mounjaro). Tirzepatide is a dual GIP/GLP-1 agonist — it works on two receptor types instead of one — and has shown greater average weight loss in head-to-head trials. Both are available as brand-name FDA-approved products and as compounded versions.
Compounded versions are made by 503A compounding pharmacies under individual-patient prescriptions. They are significantly cheaper than brand-name but are not FDA-approved as finished products. Both semaglutide and tirzepatide can be compounded legally under current rules, but the regulatory picture is actively evolving. This is the most important caveat in any GLP-1 price comparison right now.
Henry Meds — cheapest bundled compounded semaglutide
Henry Meds charges a single monthly price that includes everything: the compounded semaglutide (oral or injectable), clinician visits, lab review, and shipping. The oral version at $249/mo is currently the most affordable all-in compounded semaglutide we can verify. Unlike some competitors, the price does not change as the dose escalates.
- Pros: clear all-in pricing; no membership fee stacked on top; no dose-escalation price hikes
- Cons: compounded product, not FDA-approved as a finished drug
- Best for: women who want the lowest consistent monthly cost for compounded semaglutide
Fridays — cheapest on an annual commitment
Fridays' annual plan brings compounded semaglutide to ~$150/mo — among the lowest prices available anywhere for a full-service program. The catch is commitment: month-to-month runs $249/mo, and the discount only applies if you pay for 12 months at once. The program includes dietitian access, lifestyle coaching, and app support bundled in.
- Pros: cheapest annual rate; dietitian and coaching included; no separate membership
- Cons: annual commitment required for best price; BBB complaints about refund processes
- Best for: women committed to a year-long GLP-1 program who want the lowest possible annual cost
Curex — cheapest for compounded tirzepatide
Curex offers compounded tirzepatide at roughly $199/mo all-in — the lowest all-in tirzepatide price we can verify from a service that includes the consult and shipping in that figure. The price holds at the starter dose and should be confirmed before assuming it applies at higher titration levels.
Brand-name at the lowest accessible price: NovoCare and LillyDirect
For brand-name products, NovoCare intro pricing at $199/mo is the most affordable way in for Wegovy, but it is time-limited (two fills at starter doses) and rises significantly after. LillyDirect's self-pay vials for Zepbound start at $299/mo for the lowest dose — more expensive than compounded alternatives but the only FDA-approved tirzepatide option at this price tier.
Annual cost comparison
At ongoing maintenance doses (after the intro period), the annual cost range looks like this: Henry Meds compounded semaglutide injection = ~$3,564/yr. Fridays compounded semaglutide (annual plan) = ~$1,800/yr. LillyDirect Zepbound 5mg = ~$4,788/yr. NovoCare ongoing (Wegovy, post-intro) = ~$4,188/yr. Henry Meds oral semaglutide = ~$2,988/yr. Brand-name at retail list (no savings program) = $16,000–$19,000+/yr.
Compounding legal status: what to know in 2026
FDA has been tightening enforcement around compounded GLP-1 medications since 2025. Semaglutide is no longer on the official drug shortage list, but 503A pharmacies can still legally compound it for individual patients under a prescriber's order. Tirzepatide similarly: broad 503B outsourcing facility compounding has faced restriction, but individual-patient 503A compounding continues.
This means your compounded GLP-1 prescription can still be filled legally, but the pathway is narrower than it was in 2023–2024 when shortage-based compounding was more broadly permitted. Ask your provider specifically which pharmacy model they use and whether they have contingency plans if regulatory conditions shift.
Frequently asked questions
What is the cheapest GLP-1 available right now?+–
The cheapest all-in GLP-1 we can verify is compounded semaglutide from Fridays on an annual commitment at ~$150/mo, or Henry Meds oral semaglutide at $249/mo month-to-month. Compounded tirzepatide starts around $199/mo from Curex. All compounded options are not FDA-approved as finished products.
Is compounded GLP-1 still legal in 2026?+–
As of June 2026, compounded semaglutide and tirzepatide can still be legally dispensed by 503A compounding pharmacies filling individual prescriptions. Broad 503B outsourcing facility compounding has been more restricted. The regulatory environment has been active — confirm current status with your provider before enrolling.
Semaglutide or tirzepatide — which is cheaper?+–
Compounded semaglutide is generally cheaper than compounded tirzepatide. The price difference is roughly $50–100/mo at comparable service tiers. Brand-name tirzepatide (LillyDirect vials) is currently priced lower than brand-name semaglutide (Wegovy) at most dose levels when comparing self-pay options.
Does insurance cover any GLP-1 medications?+–
Commercial insurance varies widely. Some plans cover Ozempic for T2D and Wegovy for obesity with prior authorization; most do not cover compounded versions. Medicare Part D covers Ozempic for T2D but the Inflation Reduction Act excluded Wegovy from Medicare coverage for weight loss (as of early 2026). Verify your specific plan.
Are patient assistance programs available for GLP-1 medications?+–
Yes. Novo Nordisk's Patient Assistance Program and Lilly Cares Foundation offer free or heavily discounted brand-name medications (Wegovy and Zepbound, respectively) to uninsured patients at or below 400% of the Federal Poverty Level. Income documentation is required. Processing takes 4–6 weeks on average.